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Pyrrolizidine alkaloids (PA)
Pyrrolizidine alkaloids are secondary metabolites produced by a large number of plant species all over the world as protection against herbivores. The PA content in plants varies widely, depending on the plant species and the part of the plant, and is also influenced by other factors (e.g. climate, soil properties).
PA can lead to acute liver damage when consumed in high doses and in animal studies, some PA have proven to be genotoxic carcinogens. Therefore, PA are undesirable in food and feed due to their potentially harmful effects. The German Federal Institute for Risk Assessment (BfR) is currently conducting a research project on the "Determination of Pyrrolizidine Alkaloids in Food and Feed".
Information
(2)Date | Title | Size |
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27.01.2015 BfR Information
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Determination of pyrrolizidine alkaloids (PA) in honey by SPE-LC-MS/MS: Method Protocol |
309.2 KB |
24.10.2014 BfR Information
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Determination of pyrrolizidine alkaloids (PA) in plant material by SPE-LC-MS/MS: Method Protocol |
433.8 KB |
Opinion
(3)Date | Title | Size |
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05.07.2013 BfR Opinion No. 018/2013
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Pyrrolizidine alkaloids in herbal teas and teas |
313.6 KB |
11.08.2011 BfR Opinion No. 038/2011
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Chemical analysis and toxicity of pyrrolizidine alkaloids and assessment of the health risks posed by their occurrence in honey |
33.6 KB |
10.01.2007 BfR Opinion No 028/2007
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Salad mix contaminated with groundsel containing pyrrolizidine alkaloids |
61.8 KB |
FAQ
(1)Date | Title | Size |
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16.12.2022 Updated BfR FAQ
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Questions and Answers on Pyrrolizidine Alkaloids in Food |
77.2 KB |